1 Basics for Bioinformatics
1.1 What Is Bioinformatics
1.2 Some Basic Biology
1.2.1 Scale and Time
1.2.2 Cells
1.2.3 DNA and Chromosome
1.2.4 The Central Dogma
1.2.5 Genes and the Genome
1.2.6 Measurements Along the Central Dogma
1.2.7 DNA Sequencing
1.2.8 Transcriptomics and DNA Microarrays
1.2.9 Proteomics and Mass Spectrometry
1.2.10 ChIP-Chip and ChIP-Seq
1.3 Example Topics of Bioinformatics
1.3.1 Examples of Algorithmatic Topics
1.3.2 Examples of Statistical Topics
1.3.3 Machine Learning and Pattern Recognition Examples
1.3.4 Basic Principles of Genetics
References
2 Basic Statistics for Bioinformatics
2.1 Introduction
2.2 Foundations of Statistics
2.2.1 Probabilities
2.2.2 Random Variables
2.2.3 Multiple Random Variables
2.2.4 Distributions
2.2.5 Random Sampling
2.2.6 Sufficient Stafistics
2.3 Point Estimation
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