preface vii
acknowledgments xi
chapter i introduction to survival analysis
introduction 2
abbreviated outline 2
objectives 3
presentation 4
detailed outline 34
practice exercises 38
test 40
answers to practice exercises 42
chapter 2 kaplan-meier survival curves and the
log-rank test 45
introduction 46
abbreviated outline 46
objectives 47
presentation 48
detailed outline 70
practice exercises 73
.test 77
answers to practice exercises 79
appendix: matrix formula for the log-rank statistic
for several groups 82
chapter 3 the cox proportional hazards model and its
characteristics 83
introduction 84
abbreviated outline 84
objectives 85
presentation 86
detailed outline 117
practice exercises 119
test 123
answers to practice exercises 127
chapter 4 evaluating the proportional hazards
assumption 131
introduction 132
abbreviated outline 132
objectives 133
presentation 134
detailed outline 158
practice exercises 161
test 164
answers to practice exercises 167
chapter 5 the stratified cox procedure 173
introduction 174
abbreviated outline 174
objectives 175
presentation 176
detailed outline 198
practice exercises 201
test 204
answers to practice exercises 207
chapter 6 extension of the cox proportional hazards
model for time-dependent variables 211
introduction 212
abbreviated outline 212
objectives 213
presentation 214
detailed outline 246
practice exercises 249
test 253
answers to practice exercises 255
chapter 7 parametric survival models 257
introduction 258
abbreviated outline 258
objectives 259
presentation 260
detailed outline 313
practice exercises 319
test 324
answers to practice exercises 327
chapter 8 recurrent event survival analysis 331
introduction 332
abbreviated outline 332
objectives 333
presentation 334
detailed outline 371
practice exercises 377
test 381
answers to practice exercises 389
chapter 9 competing risks survival analysis 391
introduction 392
abbreviated outline 394
objectives 395
presentation 396
detailed outline 440
practice exercises 447
test 452
answers to practice exercises 458
computer appendix: survival analysis on
the computer 463
a. stata 465
b. sas 508
c. spss 542
test answers 557
references 581
index 585
