医学微生物学 英文改编版 第2版

本套英文改编版教材是我社组织国内一流的院士、学者，以国际有名出版公司美国McGraw-HillCo.优秀医学教材为基础，以我国教育部颁布的教学大纲为依据为来华留学生及国内双语教学量身制作的全英文医学授课教材。本套教材改编时充分考虑了学科发展及国内外医学教育的现状，结合国内医学教育和来华留学生来源国的教学需求。教材在注重课程体系完整性的同时，延续了学科内容的系统性和连贯性。本书由科学出版社和美国McGraw-HillCo.合作出版。未经出版者预先书面许可，不得以任何方式复制或抄袭本书的任何内容；否则我们将视为违反著作权法，将给予法律追究。

Chapter 1 Introduction 1
1 Bacteria 1
2 Viruses 1
3 Fungi 1
4 Chapter Summary 2
Review Questions 2
Chapter 2 Cell Structure 3
1 Prokaryotic Cell Structure 3
2 Staining 22
3 Morphologic Changes During Growth 23
4 Chapter Summary 23
Review Questions 24
Chapter 3 Bacterial Physiology 25
1 Classification of Bacteria 25
2 The Growth, Survival, and Death of Microorganisms 35
3 Cultivation of Microorganisms 41
4 Microbial Metabolism 50
5 Chapter Summary 61
Review Questions 62
Chapter 4 Bacterial Genetics 65
1 The Prokaryotic Genome 65
2 Bacteriophage 67
3 Transfer of DNA 68
4 Mutations and Selection 74
5 Applications of Bacterial Genetics 76
6 Chapter Summary 77
Review Questions 77
Chapter 5 Normal Human Microbiota 78
1 Role of the Resident Microbiota 78
2 Normal Microbiota of the Skin 79
3 Normal Microbiota of the Mouth and Upper Respiratory Tract 79
4 Normal Microbiota of the Urethra 83
5 Normal Microbiota of the Vagina 83
6 Normal Microbiota of the Conjunctiva 83
7 Chapter Summary 83
Review Questions 84
Chapter 6 Bacterial Infection and Immunity 86
1 Overview 86
2 Pathogenesis of Bacterial Infections 86
3 Immunity of Bacterial Infections 96
4 Chapter Summary 112
Review Questions 113
Chapter 7 Laboratory Diagnosis, Treatment and Prophylaxis of Bacterial Infection 116
1 Laboratory Diagnosis of Bacterial Infection 116
2 Treatment and Prophylaxis of Bac terial Infection 122
Review Questions 130
Chapter 8 Pathogenic Coccus 132
1 The Staphylococci 132
2 The Streptococci 138
3 The Entercocci 146
4 The Neisseria 147
5 Chapter Summary 152
Review Questions 153
Chapter 9 Enteric Gram-negative Rods (Enterobacteriaceae) 155
1 Classification 155
2 Diseases Caused by Enterobac teriaceae Other Than Salmonella and Shigella 159
3 The Shigellae 162
4 The Salmonella-Arizona Group 163
5 Chapter Summary 166
Review Questions 167
Chapter 10 Vibrios, Campylobacters,Helicobacter, and Associated Bacteria 169
1 The Vibrios 169
2 Campylobacter 171
Review Questions 174
Chapter 11 Spore-forming Gram-positive Bacilli: Bacillus and Clostridium Species 176
1 Bacillus Species 176
2 Bacillus Anthracis 176
3 Bacillus Cereus 178
4 Clostridium Species 179
5 Clostridium Botulinum 179
6 Clostridium Tetani 180
7 Clostridia That Produce Invasive Infections 181
8 Clostridium Difficile and Diarrheal Disease 183
Review Questions 183
Chapter 12 Infections Caused by Anaerobic Bacteria 185
1 Anaerobic Bacteria Found in Hu man Infections 185
2 Pathogenesis of Anaerobic Infec tions 187
3 The Polymicrobial Nature of Anae robic Infections 187
4 Diagnosis of Anaerobic Infections 188
5 Treatment of Anaerobic Infections 188
6 Chapter Summary 188
Review Questions 188
Chapter 13 Mycobacteria 190
1 Mycobacterium Tuberculosis 190
2 Mycobacterium Leprae 192
3 Chapter Summary 192
Review Questions 192
Chapter 14 Aerobic Non-Spore-Forming Gram-positive Bacilli 193
1 Corynebacterium Diphtheriae 194
2 Other Coryneform Bacteria 197
3 Listeria Monocytogenes 197
4 Actinomycetes 198
5 Nocardiosis 199
6 Actinomycetoma 199
7 Chapter Summary 200
Review Questions 200
Chapter 15 Pseudomonads and Acinetobacters 202
1 Pseudomonads 202
2 Acinetobacter 206
3 Chapter Summary 207
Review Questions 207
Chapter 16 Haemophilus, Bordetella,Brucella, Francisella 209
1 Haemophilus 209
2 Bordetella 210
3 Brucella 212
4 Francisella 214
5 Chapter Summary 215
Review Questions 216
Chapter 17 Yersinia and Pasteurlla 217
1 Yersinia 217
2 Pasteurella 219
Review Questions 220
Chapter 18 Legionellae, Bartonella, and Unusual Bacterial Pathogens 222
1 Legionella Pneumophila and Other Legionellae 222
2 Bartonella 223
3 Streptobacillus Moniliformis 224
4 Chapter Summary 225
Review Questions 225
Chapter 19 Spirochetes and Other Spiral Microorganisms 227
1 Treponema Pallidum and Syphilis 227
2 Borrelia Burgdorferi and Lyme Disease 229
3 Leptospira and Leptospirosis 231
Review Questions 233
Chapter 20 Mycoplasma and Cell
Wall-Defective Bacteria 234
1 General Introduction 234
2 Mycoplasma Pneumoniae 236
3 Other Pathogenic Mycoplasma 237
4 Cell Wall-Defective Bacteria 237
5 Chapter Summary 238
Review Questions 238
Chapter 21 Rickettsia and Related Genera 240
1 General 240
2 Rickettsia and Orientia 240
3 Coxiella Burnetii 243
4 Ehrlichia and Anaplasma 244
5 Chapter Summary 245
Review Questions 245
Chapter 22 Chlamydiae 247
1 General Properties of Chlamydia 247
2 Diseases 249
3 Chapter Summary 254
Review Questions 255
Chapter 23 General Properties of Viruses 257
1 Classification of Viruses 257
2 Virus Structure 258
3 Chemical Composition of Viruses 261
4 Replication of Viruses 262
5 Genetics of Animal Viruses 266
6 Natural History (Ecology) and Modes of Transmission of Viruses 268
7 Reaction to Physical and Chemical Agents 270
8 Laboratory Techniques of Virology 271
9 Chapter Summary 273
Review Questions 273
Chapter 24 Viral Infection and Immune Response to Viruses 276
1 The Modes and Types of Viral Infec tion and Pathogenicity of Viruses 276
2 Anti-Virus immunity 285
3 Chapter Summary 290
Review Questions 290
Chapter 25 Diagnosis, Treatment and Prevention of Viral Infection 292
1 Diagnosis of Viral Infection 292
2 Treatment of Viral Infection 298
3 Prevention of Viral Infection 299
4 Chapter Summary 301
Review Questions 302
Chapter 26 Orthomyxoviruses (Influenza Viruses), Paramyxoviruses and Rubella Virus 304
1 Orthomyxoviruses (Influenza Vir us) 304
2 Paramyxoviruses and Rubella Virus 314
3 Chapter Summary 331
Review Questions 332
Chapter 27 Coronaviruses and Adenoviruses 335
1 Coronaviruses 335
2 Adenoviruses 338
3 Chapter Summary 343
Review Questions 343
Chapter 28 Picornaviruses (Enterovirus and Rhinovirus Groups) 345
1 Properties of Picornaviruses 345
2 Enterovirus Group 346
3 Rhinoviruses 351
4 Other Picornaviruses 352
5 Chapter Summary 352
Review Questions 352
Chapter 29 Reoviruses, Rotaviruses and
Caliciviruses 354
1 General Properties of Reoviridae 354
2 Rotaviruses 355
3 Reoviruses and Caliciviridae 358
4 Chapter Summary 359
Review Questions 359
Chapter 30 Hepatitis Viruses 361
1 Properties of Hepatitis Viruses 361
2 Hepatitis Virus Infections in Humans 367
3 Chapter Summary 376
Review Questions 377
Chapter 31 AIDS and Lentiviruses 380
1 Properties of Lentiviruses 380
2 HIV Infections in Humans 384
3 Chapter Summary 392
Review Questions 392
Chapter 32 Herpesviruses 394
1 General Properties of Herpesvi ru ses 394
2 Herpesvirus Infections in Humans 396
3 Chapter Summary 408
Review Questions 408
Chapter 33 Arthropod-Borne and Rodent-Borne Viral Diseases 410
1 Arbovirus Infections 410
2 Hemorrhagic Fever Virus Infections 414
3 Chapter Summary 417
Review Questions 418
Chapter 34 Poxviruses and Parvoviruses 420
1 Poxviruses 420
2 Parvoviruses 426
3 Chapter Summary 430
Review Questions 430
Chapter 35 Rabies, Slow Virus Infections,and Prion Diseases 432
1 Rabies 432
2 Slow Virus Infections and Prion Dis eases 437
3 Chapter Summary 439
Review Questions 440
Chapter 36 Medical Mycology 442
1 General Property of Fungi 442
2 Pathogenic Fungi 444
3 Chapter Summary 448
Review Questions 449
Chapter 37 Cases and Clinical Correlations 452
1 Central Nervous System 452
2 Respiratory 456
3 Heart 460
4 Abdomen 461
5 Urinary Tract 463
6 Bone and Soft Tissue 468
7 Sexually Transmitted Diseases 470
8 Mycobacterium Tuberculosis In fections 472
9 HIV-1 and AIDS 475
10 Infections in Transplant Patients 479
11 Biologic Warfare and Bioterrorism 483
Chinese-English Vocabulary 488