实验动物学(英文版)

Chapter 1 Introduction of Laboratory Animal Science 1.1 History of Laboratory Animal Science 1.2 Organizations Associated with Laboratory Animal Science 1.3 Animal Welfare 1.4 Animals Used in Research, Product Safety Testing and Teaching 1.5 Regulations, Policies and Principles Governing the Care and Use of Laboratory Animals 1.6 Facility, Equipment, Housing and Management 1.7 Classifications of Animals According to the Burden of Resident Micro-organisms Chapter 2 Mice 2.1 Genetics 2.2 Ecological Types 2.3 Uses 2.4 Behavior 2.5 Anatomic and Physiologic Features 2.6 Breeding and Reproduction 2.7 Housing and Environment 2.8 Environmental Enrichment 2.9 Feeding and Watering 2.10 Sanitation 2.11 Techniques Chapter 3 Rats 3.1 Genetics 3.2 Ecologic Types 3.3 Uses 3.4 Behavior 3.5 Anatomic and Physiologic Features 3.6 Breeding and Reproduction 3.7 Housing and Environment 3.8 Environmental Enrichment 3.9 Feeding and Watering 3.10 Sanitation 3. 11 Techniques Chapter 4 Gerbils 4.1 Uses 4.2 Behavior 4.3 Anatomic and Physiologic Features 4.4 Breeding and Reproduction 4.5 Housing and Environment 4.6 Sanitation 4.7 Environmental Enrichment 4.8 Feeding and Watering 4.9 Techniques Chapter 5 Hamsters 5.1 Uses 5.2 Behavior 5.3 Anatomic and Physiologic Features 5.4 Breeding and Reproduction 5.5 Housing and Environment 5.6 Sanitation 5.7 Environmental Enrichment 5.8 Feeding and Watering 5.9 Techniques Chapter 6 Guinea Pigs 6.1 Uses 6.2 Behavior 6.3 Anatomic and Physiologic Features 6.4 Breeding and Reproduction 6.5 Housing and Environment 6.6 Sanitation 6.7 Environmental Enrichment 6.8 Feeding and Watering 6.9 Techniques Chapter 7 Rabbits 7.1 Breeds 7.2 Uses 7.3 Behavior 7.4 Anatomic and Physiologic Features 7.5 Breeding and Reproduction 7.6 Housing and Environment 7.7 Environmental Enrichment 7.8 Feeding and Watering 7.9 Sanitation 7.10 Techniques Chapter 8 Cats 8.1 Uses 8.2 Behavior 8.3 Anatomic and Physiologic Features 8.4 Breeding and Reproduction 8.5 Handling and Restraint 8.6 Identification Methods 8.7 Signs of Pain, Distress or Illness 8.8 Housing and Environment 8.9 Environmental Enrichment 8.10 Euthanasia Chapter 9 Dogs 9.1 Uses 9.2 Behavior 9.3 Anatomic and Physiologic Features 9.4 Breeding and Reproduction 9.5 Handling and Restraint 9.6 Identification Methods 9 7 Signs of Pain. Distress or Illness 9.8 Housing and Environment 9.9 Environmental Enrichment 9.10 Euthanasia Chapter 10 Pigs 10.1 Uses 10.2 Behavior 10.3 Anatomic and Physiologic Features 10.4 Breeding and Reproduction 10.5 Handling and Restraint 10.6 Identification Methods 10.7 Signs of Pain, Distress or Illness 10.8 Housing and Environment 10.9 Environmental Enrichment 10.10 Euthanasia Chapter 11 Nonhuman Primates 11.1 Strepsirrhini (Prosimians) 11.2 Haplorrhini (Tarsiers, Monkeys and Apes, Including Humans) 11.3 Uses 11.4 Behavior 11.5 Anatomic and Physiologic Features 11.6 Breeding and Reproduction 11.7 Housing and Environment 11.8 Environmental Enrichment 11.9 Feeding and Watering 11.10 Sanitation 11.11 Techniques Chapter 12 Amphibians 12.1 Anatomic and Physiologic Features 12.2 Handling and Restraint 12.3 Identification Methods 12.4 Behavior 12.5 Signs of Pain, Distress or Illness 12.6 Husbandry and Diet 12.7 Environmental Enrichment 12.8 Euthanasia Chapter 13 Animal Genetics and Breeding 13.1 Dominant and Recessive Alleles 13.2 Gene Symbols 13.3 Genotype and Pbenotype 13.4 Homozygotes and Heterozygotes 13.5 Gene Expression 13.6 Gene Linkage 13.7 Strain and Stock Nomenclature 13.8 Breeding and Reproduction 13.9 Mating Systems 13.10 Breeding Schemes 13.11 Genetic Engineering 13.12 Gene-Targeted Mutations 13.13 Applications of Transgenic Animals Chapter 14 Laboratory Techniques 14.1 Injection 'Feehniques 14.2 Blood Collection Techniques 14.3 Other Techniques Chapter 15 Research Methodology 15.1 Acute Toxicity Tests 15,2 Subchronic Toxicity Tests 15.3 Chronic Tests 15.4 Reproductive Tests 15.5 Micronucleus Tests 15.6 PyrogenTests 15.7 Induced Cancer Models 15.8 Spontaneous Cancer Models Appendix Appendix 1 The U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research and Training Appendix 2 Example of Animal Use Protocol Appendix 3 Normal Values Appendix 4 Frequently Asked Questions in Animal Research Appendix 5 Useful Web Sites for Laboratory Animal Science References