2023中国医疗器械科技创新发展报告——生物医用材料

为系统反映国内外生物医用材料科技和产业领域的发展概况和主要成果，总结发展经验、研判发展趋势，中国生物技术发展中心组织开展《2023中国医疗器械科技创新发展报告——生物医用材料》（简称《报告》）的编制工作。《报告》共分为九章：第一章介绍了生物医用材料领域科技和产业发展现状及趋势；第二章至第九章分别对心血管生物医用材料、骨科生物医用材料、口腔生物医用材料、眼科生物医用材料、神经修复医用生物材料、血液净化生物医用材料、伤口护理生物医用材料和新一代生物医用材料的市场现状、重要技术、产品研究进展、未来发展趋势等进行了详细介绍。

中国生物技术发展中心为国家科学技术部直属事业单位，主要职责是开展我国生物技术领域的战略研究和政策分析，参与国家科技规划的制定，承担科技计划项目的专业化管理，承担生物资源与生物安全管理的有关工作，推动成果转化和产业画，促进国际交流与合作。

\"目 录 第一章 生物医用材料科技和产业发展现状及趋势 ···································1 第一节 国内外生物医用材料研究发展现状 ············································2 一、科学研究现状 ·············································································2 二、成果转化 ···················································································6 三、全球重点区域发展介绍 ·································································7 第二节 国内外生物医用材料科技及产业政策 ·······································23 一、国外生物医用材料科技与产业政策 ················································23 二、中国生物医用材料科技与产业政策 ················································26 第三节 国内外生物医用材料市场现状 ················································37 一、全球生物医用材料市场分析 ·························································37 二、中国生物医用材料市场分析 ·························································42 第四节 我国生物医用材料展望 ·························································46 一、生物材料的组织诱导性 ·······························································47 二、生物材料的智能化 ·····································································48 三、生物材料的纳米化 ·····································································49 四、生物材料与生物前沿技术交叉融合 ················································50 五、生物材料与人工智能（AI）的整合 ················································51 参考文献 ·······················································································52 第二章 心血管生物医用材料 ·······························································54 第一节 心血管生物医用材料概述 ······················································54 一、心血管生物医用材料的定义 ·························································55 二、心血管生物医用材料的分类 ·························································55 第二节 心血管生物医用材料市场现状 ················································59 一、全球心血管生物医用材料的市场现状及发展趋势 ······························59 二、中国心血管生物医用材料的市场现状及发展趋势 ······························62 三、中国心血管生物医用材料细分领域的市场发展状况 ···························68 第三节 国内外重要技术和产品研究进展 ·············································75 一、冠脉支架 ·················································································75 二、心脏瓣膜 ·················································································78 三、心力衰竭治疗 ···········································································82 四、心脏封堵器 ··············································································86 第四节 心血管生物医用材料前景与展望 ·············································87 参考文献 ·······················································································89 第三章 骨科生物医用材料 ··································································90 第一节 骨科生物医用材料概述 ·························································90 一、骨科植入器械的分类 ··································································91 二、骨科生物医用材料的分类 ····························································92 第二节 骨科生物医用材料市场现状 ···················································93 一、骨科医疗器械产品市场现状 ·························································93 二、骨科生物医用原材料全球市场现状 ···············································102 三、骨科生物医用原材料中国市场现状 ···············································105 第三节 国内外重要技术和产品研究进展 ············································107 一、3D打印技术在骨科产品中的应用 ·················································107 二、可降解生物材料在骨科产品中的应用 ············································108 三、骨修复材料 ·············································································116 四、关节软骨再生/修复产品和技术 ···················································120 五、半月板修复/再生材料和产品 ······················································121 六、关节韧带修复再生材料和产品 ·····················································122 七、钽金属材料在骨科产品中的应用 ··················································123 第四节 骨科生物医用材料前景展望 ··················································124 一、组织工程与再生医学材料前沿 ·····················································125 二、新一代生物功能型医用金属材料的开发 ·········································132 三、多功能骨科植入材料及器械 ························································134 参考文献 ······················································································136 第四章 口腔生物医用材料 ·································································138 第一节 口腔生物医用材料概述 ························································138 第二节 口腔生物医用材料市场现状 ··················································140 一、国际口腔生物材料市场现状 ························································140 二、国内口腔生物材料市场情况 ························································143 第三节 国内外重要技术和产品研究进展 ············································162 一、口腔充填修复材料 ····································································162 二、口腔义齿制作材料 ····································································165 三、口腔植入材料 ··········································································171 四、其他 ······················································································179 第四节 国内口腔医疗器械前景展望 ··················································184 一、口腔数字化材料发展迅速 ···························································185 二、人工智能技术发展迅速 ······························································186 三、隐形正畸发展迅速 ····································································186 参考文献 ······················································································187 第五章 眼科生物医用材料 ·································································189 第一节 眼科生物医用材料概述 ························································189 一、眼科生物医用材料类及特点 ·····················································190 二、眼科生物医用材料发展 ······························································191 三、眼科生物医用材料市场规模及主要生产企业 ···································193 第二节 眼科生物医用材料市场现状 ··················································197 一、视光及屈光不正治疗材料 ···························································197 二、白内障治疗材料 ·······································································206 三、角膜病治疗材料 ·······································································209 四、青光眼治疗材料 ·······································································211 五、玻璃体及视网膜治疗材料 ···························································213 第三节 国内外重要技术和产品研究进展 ············································214 一、硬性接触镜 ·············································································214 二、软性接触镜 ·············································································219 三、人工晶状体 ·············································································219 四、人工角膜 ················································································226 五、人工玻璃体 ·············································································229 六、青光眼引流装置 ·······································································230 第四节 眼科生物医用材料前景与展望 ···············································232 一、眼科生物医用材料的前沿方向 ·····················································233 二、眼科生物医用材料发展趋势 ························································239 参考文献 ······················································································240 第六章 神经科修复生物医用材料 ·······················································243 第一节 神经科修复生物医用材料概述 ···············································243 第二节 神经科修复生物医用材料市场现状 ·········································245 一、神经外科修复材料 ····································································245 二、周围神经损伤修复材料市场现状 ··················································250 三、脊髓损伤修复材料 ····································································252 第三节 国内外重要技术和产品进展 ··················································255 一、神经外科修复材料 ····································································255 二、周围神经损伤修复材料 ······························································257 三、脊髓损伤修复材料 ····································································265 第四节 神经科修复生物医用材料前景与展望 ······································275 一、类器官 ···················································································276 二、中枢神经系统的药物递送 ···························································277 三、脑机接口界面材料 ····································································279 参考文献 ······················································································282 第七章 血液净化生物医用材料 ···························································284 第一节 血液净化医用材料概述 ························································284 一、血液净化生物医用材料的定义 ·····················································285 二、血液净化生物医用材料的分类 ·····················································285 三、血液净化生物医用材料的基本要求 ···············································286 四、血液净化生物医用材料的国内外情况 ············································286 第二节 血液净化生物医用材料市场现状 ············································287 一、血液净化生物医用材料总体市场状况 ············································288 二、血液净化医用透析材料市场现状 ··················································289 三、血液灌流材料市场现状 ······························································294 第三节 血液净化材料重要技术和产品研究进展 ···································301 一、透析膜技术重要进展 ·································································301 二、血液灌流材料技术重要进展 ························································303 三、国内外重要产品研究进展 ···························································304 第四节 血液净化医用材料前景与展望 ···············································307 一、血液净化医用材料的前景 ···························································308 二、血液净化医用材料的展望 ···························································309 参考文献 ······················································································310 第八章 创面修复生物医用材料 ···························································311 第一节 创面修复生物医用材料概述 ··················································311 第二节 创面修复生物医用材料市场现状 ············································313 一、创面修复生物医用材料全球市场现状 ············································313 二、国际生物医用材料代表性企业介绍 ···············································315 三、创面修复生物医用材料中国市场现状 ············································317 第三节 国内外创面修复生物医用材料重要技术和产品研究进展 ··············322 一、临床适应证产品概述 ·································································322 二、止血材料与技术 ·······································································324 三、创面封闭材料与技术 ·································································332 四、创面修复技术与产品 ·································································333 五、皮肤组织替代物 ·······································································339 第四节 创面修复生物医用材料前景与展望 ·········································341 一、功能化/智能化创面修复材料 ······················································342 二、创面修复新型技术 ····································································343 三、结语 ······················································································345 参考文献 ······················································································345 第九章 新一代生物医用材料 ·································