Section I Neurobiology of Pain
Chapter 1 Peripheral Mechanisms of Cutaneous Nociception
Chapter 2 Molecular Biology of Sensory ransduction
Chapter 3 Infl ammatory Mediators and Modulators of Pain
Chapter 4 Microglia: Critical Mediators of Pain Hypersensitivity after Peripheral Nerve Injury
Chapter 5 Neuroanatomical Substrates of Spinal Nociception
Chapter 6 Spinal Cord Plasticity and Pain
Chapter 7 Representation of Pain in the Brain
Chapter 8 Central Nervous System Mechanisms of Pain Modulation
Chapter 9 Development of Pain Pathways and Mechanisms
Chapter 10 Genetics of Pain
Chapter 11 Animal Models of Pain
Chapter 12 Ascending Projection Systems
Chapter 13 Autonomic, Endocrine, and Immune Interactions in Acute and Chronic Pain
Chapter 14 Itch
Section II Assessment and Psychology of Pain
Chapter 15 Gender Differences in Pain and Its Relief
Chapter 16 Epidemiology of Pain
Chapter 17 Emotion, Motivation, and Pain
Chapter 18 Cognitive and Learning Aspects
Chapter 19 Psychiatric Pain-Associated Co-morbidities
Chapter 20 Studies of Pain in Human Subjects
Chapter 21 Pain Measurement in Adult Patients
Chapter 22 Pain in Older Persons
Chapter 23 Measurement and Assessment of Pediatric Pain
Chapter 24 Assessment of Pain Beliefs,Coping, and Function
Chapter 25 Hypnotic Analgesia
Chapter 26 Pain, Opiates, and Addiction
Chapter 27 Placebo Analgesia
Section III Pharmacology and Treatment of Pain
Chapter 28 Spinal Pharmacology of Nociceptive Transmission
Chapter 29 Methods of Therapeutic Trials
Chapter 30 Opioids: Basic Mechanisms
Chapter 31 Opioids: Clinical Use
Chapter 32 Cyclooxygenase Inhibitors: Basic Aspects
Chapter 33 Cyclooxygenase Inhibitors: Clinical Use
Chapter 34 Antidepressant Analgesics
Chapter 35 Mechanism of Action of Anticonvulsants as Analgesic Drugs
Chapter 36 Anticonvulsants: Clinical
Chapter 37 Local Anesthetic Blocks and Epidurals
Chapter 38 Cannabinoids
Chapter 39 Analgesic Drugs in Development
Chapter 40 Neurosurgical Approaches to the Treatment of Pain
Chapter 41 Spinal Cord and Brain Stimulation
Chapter 42 The Cognitive-Behavioral Approach to Pain Management
Chapter 43 A Critical Appraisal of Complementary and Alternative Medicine
Section IV Clinical States/Deep Somatic Tissue
Chapter 44 Joint Pain: Basic Mechanisms
Chapter 45 Basic Mechanisms of Muscle Pain
Chapter 46 Postoperative Pain and Its Management
Chapter 47 Osteoarthritis and Rheumatoid Arthritis
Chapter 48 Fibromyalgia Syndrome and Myofas Pain Syndrome
Chapter 49 Low Back Pain
Chapter 50 Non-specifi c Arm Pain
Section V Clinical States/Viscera
Chapter 51 Visceral Pain: Basic Mechanisms
Chapter 52 Thoracic Pain
Chapter 53 A Clinical Perspective on Abdominal Pain
Chapter 54 Genitourinary Pain
Chapter 55 Obstetric Pain
Section VI Clinical States/Headache and Fa Pain
Chapter 56 Trigeminal Mechanisms of Nociception
Chapter 57 Acute and Chronic Orofa and Dental Pain
Chapter 58 Migraine and the Trigeminal Autonomic Cephalalgias
Chapter 59 Tension-Type Headache
Chapter 60 Pain in and around the Eye
Section VII Clinical States/Neuropathic Pain
Chapter 61 Neuropathic Pain: Pathophysiological Response of Nerves to Injury
Chapter 62 Animal Models of Experimental Neuropathic Pain
Chapter 63 Central Consequences of Peripheral Nerve Damage
Chapter 64 Phantom Limb
Chapter 65 Painful Peripheral Neuropathies
Chapter 66 Trigeminal and Glossopharyngeal Neuralgia
Chapter 67 Complex Regional Pain Syndromes
Chapter 68 Pain Following Spinal Cord Injury
Chapter 69 Central Pain
Chapter 70 Pharmacological Therapy of Neuropathic Pain
Chapter 71 Surgery for Back and Neck Pain (Including Radiculopathies)
Section VIII Clinical States/Cancer Pain
Chapter 72 Cancer Pain: Causes,Consequences, and Therapeutic Opportunities
Chapter 73 Cancer Pain Assessment and Syndromes
Chapter 74 Analgesic Therapy and Palliative Care in Children
Chapter 75 Cancer Pain: Treatment Overview
Chapter 76 Pain Control in the Care of the Dying